2015 Mercedes-Benz S-Class fuel economy

The 2015 Mercedes-Benz S-Class is rated at 15–26 MPG combined by the EPA, from 15 MPG (6.0 L 12-cyl turbo, Automatic 7-spd, Rear-Wheel Drive) to 26 MPG (3.0 L 6-cyl turbo, Automatic 7-spd, Rear-Wheel Drive). EPA size class: Large Cars, Compact Cars.

MPG by version

VersionCityHwyComb.L/100 kmUK MPGFuel cost/yr*
S550e
3.0 L 6-cyl turbo, Automatic 7-spd, Rear-Wheel Drive · Plug-in hybrid · Premium Gasoline
243026 9.031 $3,150
S550
4.7 L 8-cyl turbo, Automatic 7-spd, Rear-Wheel Drive · Premium Gasoline
172620 11.824 $4,100
S550 4matic
4.7 L 8-cyl turbo, Automatic 7-spd, 4-Wheel Drive · Premium Gasoline
162619 12.423 $4,350
S550 4matic Coupe
4.7 L 8-cyl turbo, Automatic 7-spd, 4-Wheel Drive · Premium Gasoline
162419 12.423 $4,350
S63 AMG 4matic
5.5 L 8-cyl turbo, Automatic 7-spd, 4-Wheel Drive · Premium Gasoline
152318 13.122 $4,550
S63 AMG 4matic Coupe
5.5 L 8-cyl turbo, Automatic 7-spd, 4-Wheel Drive · Premium Gasoline
152318 13.122 $4,550
S600
6.0 L 12-cyl turbo, Automatic 7-spd, Rear-Wheel Drive · Premium Gasoline
132116 14.719 $5,150
S65 AMG
6.0 L 12-cyl turbo, Automatic 7-spd, Rear-Wheel Drive · Premium Gasoline
132015 15.718 $5,500
S65 AMG Coupe
6.0 L 12-cyl turbo, Automatic 7-spd, Rear-Wheel Drive · Premium Gasoline
132015 15.718 $5,500

* EPA estimate of yearly fuel (or electricity) cost for 15,000 miles with 55 % city driving, at the fuel prices EPA used for this model year. Use the fuel cost comparison with your own mileage and prices.

About these numbers

EPA ratings come from standard laboratory tests adjusted to reflect real-world driving, so they are best for comparing vehicles. Your own figure will vary with speed, temperature, load, tires and driving style — measure it with the MPG calculator. If you have fitted larger tires, correct the reading with the tire size and fuel economy calculator.

Source: U.S. Environmental Protection Agency and U.S. Department of Energy, fueleconomy.gov. Original data (downloaded 2026-09-29). Data processed by us; errors in processing are ours, not the publisher's.