2010 Toyota Sienna fuel economy
The 2010 Toyota Sienna is rated at 18–19 MPG combined by the EPA, from 18 MPG (3.5 L 6-cyl, Automatic 5-spd, All-Wheel Drive) to 19 MPG (3.5 L 6-cyl, Automatic 5-spd, Front-Wheel Drive). EPA size class: Minivan - 2WD, Minivan - 4WD.
MPG by version
| Version | City | Hwy | Comb. | L/100 km | UK MPG | Fuel cost/yr* |
|---|---|---|---|---|---|---|
| Sienna 2WD 3.5 L 6-cyl, Automatic 5-spd, Front-Wheel Drive · Regular Gasoline | 17 | 23 | 19 | 12.4 | 23 | $3,550 |
| Sienna 4WD 3.5 L 6-cyl, Automatic 5-spd, All-Wheel Drive · Regular Gasoline | 16 | 21 | 18 | 13.1 | 22 | $3,700 |
* EPA estimate of yearly fuel (or electricity) cost for 15,000 miles with 55 % city driving, at the fuel prices EPA used for this model year. Use the fuel cost comparison with your own mileage and prices.
About these numbers
EPA ratings come from standard laboratory tests adjusted to reflect real-world driving, so they are best for comparing vehicles. Your own figure will vary with speed, temperature, load, tires and driving style — measure it with the MPG calculator. If you have fitted larger tires, correct the reading with the tire size and fuel economy calculator.
Source: U.S. Environmental Protection Agency and U.S. Department of Energy, fueleconomy.gov. Original data (downloaded 2026-09-29). Data processed by us; errors in processing are ours, not the publisher's.